Annoyance

The insensitive comment really rubbed him the wrong way.

The criticism from her colleague really got his back up.

I’ve had it with this unreliable service.

He always seems to get up on the wrong side of bed and starts the day in a grumpy mood.

He whistles constantly and it gets on Charlotte's nerves.

Don't talk to him right now; he's in a foul mood, cross as a bear with a sore head.

I'm really cheesed off about the constant interruptions during our meetings.

I'm really browned off by the constant delays in public transportation.